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However, the results varied because researchers used different wavelengths, light intensities, and session lengths in their studies (Korada et al., 2022)

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What this tail actually does in practice Initial binding to the cell surface via electrostatic interactions Internalization through a mixture of: direct translocation (rare but possible with strong polyArg motifs) endocytosis (the dominant route for most CPPs) Partial endosomal escape PolyArg motifs can destabilize endosomal membranes, but escape efficiency varies widely

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