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Compliance with ethical standards Clinical Trials Registry: CTRI/2021/01/030204

Chronic estrogen deficiency causes gastroparesis by altering neuronal nitric oxide synthase function

[2] The MHRA Drug Safety Update (August 2022) advises healthcare professionals to consider testing vitamin B12 levels in patients taking metformin who develop symptoms of neuropathy or anaemia, and to consider periodic monitoring in those at risk of deficiency