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As soon as I had these I immediately came up with small bumps all over my forehead, chin and chest

You may feel a mild pinch or pressure at the injection site, but discomfort is minimal and subsides quickly

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Initial response time also depends on: Severity of the B12 deficiency Frequency of injections Underlying health conditions Absorption and metabolism differences If youre getting your first B12 shot, your provider may start you on a more aggressive schedule, such as weekly injections until your levels are normalized