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Experimental studies have demonstrated that the glycolytic inhibitor 2-deoxyglucose can activate autophagy through the upregulation of SIRT3 and phosphorylated AMPK, reducing apoptosis in both sepsis-induced TEC injury models and LPS-stimulated HK-2 cells, ultimately improving cell viability (Tan et al., 2020

"So they might just go online, find a random company that will ship it to their house, where they don't even know what dose of the medication they're taking, or even if the medicine is safe for them as the patient with the medical conditions they have," she said

National Library of Medicine, Accessed 20 Aug