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Genetically encoded rxYFP or roGFP2 probes have also become extremely valuable tools for noninvasive, ratiometric real-time redox measurements in various compartments, cells, and organisms 64,65,66,67,68,69,70,71

By introducing pre-formed, active glutathione directly into the bloodstream, it bypasses the energy-intensive cellular synthesis process that is often impaired in ME/CFS and Long COVID

Its single-compound structure makes it easier to standardize dosing, track outcomes, and attribute observed effects to a specific mechanism

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