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The weight loss effect is most likely caused by Byetta delaying gastric emptying

The timeline for retatrutide effects including cardiovascular adaptation makes this a temporary concern during the treatment initiation period rather than a permanent cardiovascular burden

Can I restart without consulting my doctor

Patients with type 1 or type 2 diabetes, glycated hemoglobin A1c of 6.5% or higher at screening, recent diabetes medication use, or recent weight-loss medication use were excluded from the trial