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We next focused on astrocytes, important integrators of both neuronal activity and inflammatory signaling

These effects are attributable to redox regulation by SFN, since (i) SFN induced ROS and in parallel GSH depletion in primary human T-cells and (ii) thiol-containing antioxidants abolished the immunosuppressive effect of SFN

A GSH concentration gradient was evaluated at pH 8 with 100 mM NaCl using two types of 37C infection harvest materials: a microcarrier harvest material produced with serum during infection, and iCELLis harvest material produced without serum during infection, where an in increased proportion of empty capsids bound to the GSH ligand

Nishi et al., 2015