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However, such observations cannot establish causation and likely reflect the natural benefits of weight loss through any means rather than a specific drug effect

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Improved insulin sensitivity changes how your cells process glucose, and weight loss may lower your resting metabolism, meaning your body burns fewer calories at rest

On predictions that the drugs might make healthcare costs go down If you think about improving weight, that should lead to reductions in spending, and that's what many cost projection studies actually predict, is that as you get lighter, there's a gradient between obesity and spending