The Japan Society for the Study of Obesity has repeatedly issued statements that "this drug should not be used for obesity without health problems (simple obesity), and use for slimming purposes in underweight individuals is strictly prohibited." In recent years, in particular, easy weight loss methods called "GLP-1 diets" have been praised on social media and at cosmetic clinics, and cases of individuals importing and self-administering Ozempic (semaglutide), which is originally a diabetes drug, have been reported, becoming a social problem j
In addition to the molecules identified in this review to target pDNA and mRNA to the brain, several other molecules have been used to deliver different active molecules into brain, which could be applicable to the delivery of nucleic acids
We support this where indicated and provide our consultation notes for the receiving team
[DOI] [PubMed] [Google Scholar] 35.Nathan DM, Buse JB, Davidson MB, et al