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Niacinamide works to enhance skin clarity and even out skin tone, while Vitamin E delivers antioxidant nourishment for healthy-looking skin

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Potential muscle loss : GLP-1s can cause lean mass loss alongside fat loss

More serious but rare safety considerations include pancreatitis (discontinue if suspected), gallbladder disease, potential thyroid C-cell tumors (based on rodent studies), risk of hypoglycemia when used with insulin or sulfonylureas, and potential for acute kidney injury with severe dehydration