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GLP-1: Addresses GLP-1 directly addresses the underlying mechanism GLP-1 does not meaningfully address this type GLP-1 medications directly address three of these five: inflammatory, metabolic, and neurological/traumatic

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A major real-world study published in early 2026 led by researchers at Johns Hopkins Bloomberg School of Public Health and analysing electronic health records from approximately 175,000 people with T1D in the US found that those taking GLP-1 drugs had a roughly 15% lower five-year risk of major cardiovascular events and a 19% lower risk of end-stage kidney disease, without any increase in hospitalisation for DKA or severe hypoglycemia