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PubMed Central, Li, Ying, et al

Compounded: Wegovy and Zepbound are FDA-approved medications that underwent FDA review for safety, effectiveness, and manufacturing quality

Figure 2 In the SMFA assay, using blood with gametocytes pre-exposed to MB for six hours (SMFA assay), the infection rate and intensity were extremely reduced ( Figures 2D, E ), thus showing high inhibition in all tested concentrations (5 M 82.7%, 10 M 94.8%, and 20 M 100.0%) with a total blocking of transmission at the highest concentration

The team hypothesizes that the variant alters the structure of the receptor protein, leading to higher expression of receptors on the cell surface and thus better drug binding