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As PDAC flourishes and overtakes the pancreas parenchyma, the pancreatic endocrine system is prone to destruction in the form of -cell dysfunction and loss ( Figure 3 ) (81, 82), with clinical evidence of remnant pancreas volume loss leading to -cell dysfunction as diabetes status progressed from normal, prediabetic to NOD secondary to PDAC (83)

In autoimmune disease, your immune system sends antibodies to attack your own body cells, mistaking them for an infection

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