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While the majority (67.7%) of rhythmic transcripts in at least 1 genotype demonstrated unaltered rhythm (system-driven transcripts), 16.7% of transcripts lost their rhythmicity in cKOt mice (BMAL1-driven transcripts), 9.2% gained rhythmicity (transcripts that became rhythmic after the deletion of Bmal1 ), and 6.4% exhibited altered rhythm (BMAL1-modulated transcripts) (Figure 1B and Supplemental Figure 1B)

The duration of the effects can vary based on the individual and the condition being treated

Toulis KA, Anastasilakis AD, Tzellos TG et al (2010) Selenium supplementation in the treatment of Hashimotos thyroiditis: a systematic review and a meta-analysis

Last reviewed: May 28, 2026 Last updated: May 28, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations