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Beyond gastrointestinal effects, the following safety signals and class-relevant cautions warrant attention: Heart rate elevation: Retatrutide's glucagon receptor agonism has been associated with modest increases in resting heart rate in Phase 2 data

Patients were excluded if they took non-steroidal anti-inflammatory drugs (NSAIDs), any change in the dose, type, or frequency of DMARDs, consumed alcohol, had other autoimmune diseases, kidney disorders, pancreatitis, gallstones, or cancer, followed special diets in the past three months, or had recent medication changes

No pharmacokinetic interactions (meaning one affecting the blood levels of the other) are documented between Bacopa and common ADHD drugs