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According to studies, supplementation of CrP may be the direction of treating insulin resistance, glycemic control, and metabolic status in women with PCOS [137]

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Long-term adjustments may include: Switching from semaglutide to tirzepatide for greater metabolic effect Reducing medication dose once hunger cues stabilize Adding an adjunct oral medication during cravings or increased stress Transitioning to bariatric surgery when medications alone are insufficient Using medication intermittently after reaching the goal weight These decisions are made collaboratively and always prioritize wellness, safety, and long-term stability rather than quick or temporary results

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