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Focusing on the key principles of disease staging shared across several areas of medicine, this Review highlights the potential for in vivo staging of AD to transform our understanding of preclinical AD, refine enrolment criteria for trials of disease-modifying therapies and aid clinical decision-making in the era of anti-amyloid therapeutics

Its essential to follow the correct dosing and preparation procedures to avoid complications

The evidence for GHK-Cu receptor desensitization is weak

Its important to report signs of serious adverse effects, including symptoms suggesting pancreatitis or gallbladder disease, and to review interactions with other diabetes or weight-management medications