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Ophthalmic Ophthalmic abnormalities can be observed on slit lamp examination and include: KayserFleischer rings : copper deposits in Descemets membrane, appearing as rusty-brown rings in the corneas Sunflower cataracts : copper deposits affecting the lens Neurological Neurological features of Wilsons disease may include: Ataxia Dystonic syndrome: involuntary muscle contractions resulting in abnormal, sometimes painful positions 6 Akinetic-rigid syndrome: resembling the movements seen in Parkinsons disease Hepatic A thorough abdominal examination is crucial when suspecting Wilsons disease

Role of protein -SH groups in redox homeostasis--the erythrocyte as a model system

TMB substrate turned solution blue, then yellow with stop solution