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Also, smokers were more likely to have symptoms similar to COVID-19, such as cough and sputum, making them more likely to accept SARS-CoV-2 testing, even if they may not be infected, this included with the object selection bias would increase the negative samples detection rate, creating a bias ( Smoking and COVID-19 Disease Prognosis In April 2020, the WHO announced that smokers were more likely to develop serious illness from COVID-19 than non-smokers (World Health Organization, 2020b)

It can increase heart rate and blood pressure slightly, but when used responsibly, it doesnt cause the catastrophic health outcomes associated with cigarettes

Metabolic Screening: Blood tests check for thyroid dysfunction, vitamin deficiencies (specifically B12), and glucose levels to address systemic causes