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Introduction In 2009, approximately 20% (~60 million) of Americans smoked and about ~88 million non-smokers were exposed to secondhand smoke ( Nicotinic acetylcholine receptors (nAChRs) are a family of ionotropic receptor proteins formed by five homologous or identical subunits and are involved in signal transduction between neurons and muscle cells ( NAFLD Is Highly Prevalent in Obese Individuals and Can Be Exaggerated by Smoking Non-alcoholic fatty liver disease is the most common liver disorder and is associated with metabolic syndrome and diabetes mellitus

The sense of relaxation and calm from smoking is partly generated by dopamine release in the brain which rewards you with a feel-good boost or sense of relief from the tension of withdrawal each time you smoke

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Clearly cessation is more desirable than replacement therapy