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Studies were included in the subgroup analysis if they assessed the risk of cancer in different age groups, sex, gender, sexual orientation, race, ethnicity, indigenous identity, pregnant/postpartum population, education level, individual or household income, occupation, or employment status in the sample

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The inhalation of any substances can be harmful to youth, but the use of nicotine products that is particularly concerning

To the best of our knowledge, there has been no study that provides a systematic analysis of these identified SA-DNAm loci with the system biology approach for smoking behavior